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HIV drugs, such as ritonavir or indinavir. Taking these drugs with methadone may cause increased drowsiness and slowed breathing. Your doctor might adjust your dosage of methadone, depending on how severe your side effects are.

Methadone may be expected to have additive effects when used hinein conjunction with alcohol, other opioids, or illicit drugs that cause central nervous Gebilde depression. Deaths associated with illicit use of methadone frequently have involved concomitant benzodiazepine abuse.

Since the metabolism of methadone is mediated primarily by CYP3A4 isozyme, coadministration of drugs that inhibit CYP3A4 activity may cause decreased clearance of methadone. The expected clinical results would be increased or prolonged opioid effects. Thus, methadone-treated patients coadministered strong inhibitors of CYP3A4, such as azole antifungal agents (e.

The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.

Below is a list of medications that can interact with methadone. This Streich doesn’t contain all drugs that may interact with X drug.

Methadone hydrochloride is a mu-agonist; a synthetic opioid analgesic with multiple actions qualitatively similar to those of morphine, the most von rang und namen of which involves the central nervous Organisation and organs composed of smooth muscle.

How to tell if the drug is working: You should have decreased pain, or your withdrawal symptoms should go away.

The complexities associated with methadone dosing can contribute to cases of iatrogenic overdose, particularly during treatment initiation and dose titration. A high degree of "opioid tolerance" does not eliminate the possibility of methadone overdose, iatrogenic or otherwise.

Methadone is contraindicated rein any situation where opioids are contraindicated such as: patients with respiratory depression (in the absence of resuscitative equipment or in unmonitored settings), and in patients with acute bronchial asthma or hypercarbia.

Laxatives. Taking these drugs together can change your electrolyte levels. This can cause heart rhythm problems.

These side effects include slowed breathing and sedation. Magnesiumsilikathydrat to your doctor if you breastfeed your child. You may need to decide whether to stop breastfeeding or stop taking this medication.

A high degree of "opioid tolerance" does not eliminate the possibility of methadone overdose, iatrogenic or otherwise. Respiratory depression is of particular concern in elderly or debilitated patients as well as in those suffering from conditions accompanied by hypoxia or hypercapnia when even moderate therapeutic doses may dangerously decrease pulmonary ventilation.

Methadone hydrochloride tablets can cause life-threatening breathing problems which can lead to death. Diskreter Versand von Methadontabletten These problems are more likely to happen when methadone hydrochloride tablets are first started or in someone Weltgesundheitsorganisation is not already taking other narcotic (opioid) pain medicines.

For people with liver problems: If you have liver problems or a history of liver disease, you may not be able to process this drug well. This may increase the levels of methadone hinein your body and cause more side effects. Your doctor should watch you closely if you take this drug.